1. I’m certain David’s told you his business troubles. _________, it’s no secret that he owes a lot of money to the bank.
A. However B. Anyway C. Therefore D. Though
变式1：I might fail, but _________ I insist on doing it. I don’t mind it
A. however B. anyhow C. got D. meanwhile
变式2：--- I can give you a lift.
--- No, I’ll walk. _______.
A. Thanks anyway B. Never mind
C. Mind you own business D. I couldn’t agree more
解析：B 本题考查前后句的逻辑关系，前半句说“我确信Divid告诉你他的生意上的麻烦”，后半句是“众人皆知，他欠银行一大笔钱”，可以推知后半句是对前半句的补充说明。所以用anyway（无论如何）。However表示“转折”；therefore表示“结论”；though表示“尽管”。
变式1：B anyhow意为“无论怎样”。
变式2：A A选项为“不管怎样都谢谢你”；B选项为“不要紧”；C选项为“管好自己的事”；D选项为“非常赞同”。
